From a practical, work efficiency perspective, many of the people we see are prescribed similar combinations of medications and so we find we’re frequently repeating ourselves. For my clinical practice I created a file called Regular Notes, in which I templated much of the repeatable content with identifiers for the bits requiring change (people names,

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Calcium carbonate is a commonly prescribed therapeutic intervention and is listed on the Pharmaceutical Benefits Scheme (PBS). However, there is increasing concern regarding the therapeutic effectiveness of calcium carbonate when there is concurrent administration of a proton pump inhibitor (PPI).Calcium is primarily absorbed throughout the intestines and predominantly from the duodenum and jejunum.Calcium carbonate.Calcium carbonate

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Money and nutrients have some surprising commonalities –similar income/intake on a relatively regular basis,other income/intake on a regular basis,regular costs,pleasure costs.Money management typically starts with a budget – with a defined portion of money being allocated to various accounts such as regular bills, mortgage/loan repayments, Xmas/holidays, savings, and what’s left, and possibly a bit more,

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Commonly the pre-breakfast BSLs may be the only routine monitoring strategy for those with long term diabetes and deemed relatively stable. Further, commonly, if the pre-breakfast BSL is within acceptable range then further daily monitoring is rarely considered. Therefore, those people with diabetes and who are also prescribed prednisolone may be experiencing regular afternoon hyperglycaemia

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Some people can be prescribed medications from a very young age eg diabetes, epilepsy, and will consume a range of medications for most of their lives ie for decades. As the limited research indicates there are potentially many significant negative impacts that some of these longterm drugs may have on nutrient status and consequently health

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Call for emergency action to limit global temperature increases, restore biodiversity, and protect health: Wealthy nations must do much more, much faster is the headline in a recent AJCN (The American Journal of Clinical Nutrition, Volume 114, Issue 4, October 2021, Pages 1267–1269, https://doi.org/10.1093/ajcn/nqab281).It sounds great, but …This editorial is a reflection about a recent

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“Can you see Mr EYOM (Eighty Year Old Man) – he’s been losing weight?”The weight graph showed a stable weight until a defined moment when the loss was dramatic – steep enough to abseil down.The standard causes were excluded – no amputation, no gastro, no unwellness, no hospitalization, no falls, no nasty wound, no bad

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Iron supplements are generally prescribed if serum iron levels are low. Poorly absorbed iron, typically from sources such as iron supplements, results in increased iron availability to the gut microbiota with consequentincrease in the virulence of faecal enteropathogens,increase in the ratio of faecal enteropathogens to protective microbiota such as bifidobacteria and lactobacillus,favouring of the colonisation

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Nutrition research, including pharmaconutrition, is an interesting and challenging field, with an added dimension that is not essential to any other area of research – the reversibility/irreversibility component of physiological response that is integral to all findings. Do you want to be someone who contributes to good quality research in the area of pharmaconutrition and

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Because chlorpromazine (a phenothiazine), imipramine (a tricyclic acid) and amitriptyline (a tricyclic acid) have a very similar structures to riboflavin there was concern that these drugs may adversely affect riboflavin status. In fact, animal research in 1981 found that they do have a negative impact on riboflavin status. However, there has been no follow-up research

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In the early 1990s a Canadian research team was investigating whether alcohol interacted with nifedipine/felodipine and unexpectedly found that the effects of these drugs were altered by concurrent intake with grapefruit juice – this was a seminal finding. Three questions arise from this findingwhat ingredient or ingredients caused the response in the grapefruit-drug interaction?which other

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Drug-food interaction advice is quite inconsistent and falls into three main groups – advice not provided, food contra-indicated, and advice yet-to-be-determined.  Examples of advice not provided include:typically, advice is only given to abstain from alcohol intake whilst consuming antibiotics and yet there is an extensive range of drugs whereby alcohol intake is contra-indicated;a low-salt diet no

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Confusion, falls or has poor balance, insomnia, and lethargy – would you immediately be trying to decide if this person is deficient in biotin or pantothenic acid? When I raised this at a Medication Advisory Committee meeting, all the committee members (GP, Clinical Care Co-ordinator, supplying pharmacist, Accredited Pharmacist) looked at me in amazement that

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Abnormally high B12 levels are typically due to a medical disorder, however this article is specifically about elevated B12 levels due to ongoing therapeutic B12 interventions.Vitamin B12 interventions are commenced upon diagnosis of low B12 status, typically comprise high dose injections until levels are within acceptable range, and then the intervention is changed to a

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Twenty years ago, this was a very short list! Of necessity this list has grown as there has been minimal research to address these and other questions. This is the first of a monthly 3-part series.Nutrition research, including pharmaconutrition, is an interesting and challenging field, with an added dimension that is not integral to any

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Maximising drug dose or minimising side effects were the only interactions that pharmaceutical companies considered in relation to food until the early 1990s. Then the grapefruit response was discovered – and increased awareness that foods may interact with drugs.Whilst many questions arise out of the drug-food interaction topic there seem to be two key questions:which

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