Mechanisms and consequencesThe levodopa + carbidopa and vitamin D interaction is apparently additive however the evidence is limited. Given Parkinson’s ...
March 4, 2024
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- Author: Yvonne Coleman
February 19, 2024
Mechanisms and consequencesLevodopa + carbidopa and zinc interactions are a surprisingly relatively recent finding. Levodopa is both a pharmaceutical and ...
February 5, 2024
Mechanisms and consequencesIs there evidence of a levodopa + carbidopa and manganese interaction? The total metal content and cellular compartmentalization of ...
January 29, 2024
Mechanisms and consequencesThe levodopa + carbidopa, magnesium and vitamin C interaction has only recently gained recognition. Levodopa is commonly prescribed ...
December 19, 2023
Mechanisms and consequencesInteractions between aspirin and various nutrients have been identified over a number of decades and are either old, ...
December 13, 2023
Mechanisms and consequencesAn aspirin-folic acid interaction was a recent “incidental finding” from a pooled analysis of some studies looking at ...
December 4, 2023
Mechanisms and consequencesThe aspirin-vitamin C interaction was discovered in the early 1970’s. The evidence is predominantly based on short term, ...
November 27, 2023
Mechanisms and consequencesOsmolality seems to be a rarely-considered contributor to a range of primarily gastro-intestinal side effects. It is probably ...
October 16, 2023
Mechanisms and consequencesNot to be crushed, chewed, broken or dissolved and its many variations are commonly included in most Product ...
October 3, 2023
Mechanisms and consequencesExcipients are the ingredients that comprise about 90% of a medicine - they are added to optimise some ...
September 18, 2023
Mechanisms and consequences“Not clinically relevant”, “inhibition unlikely at therapeutic interventions”, “clinical inhibition deemed minimal”, and similar other phrases typically refer ...
September 11, 2023
Mechanisms and consequencesThe side effects of many prescribed medicines include altered glycaemic status which is associated with physical harm to ...
August 1, 2023
Mechanisms and consequencesMultidrug resistance proteins (MRPs) are efflux transporters and as such are responsible for the movement of a wide ...
July 24, 2023
Guest case studyGuest case study - hypercalcaemia is based on a question from a concerned clinician.Oral calcium intake - no ...
July 10, 2023
Mechanisms and consequencesOATs(Organic Anion Transporters) are primarily influx transporters albeit some are bidirectional. They can transport a wide variety of ...
June 26, 2023
Mechanisms and consequencesOATPs (Organic Anion Transporting Proteins) are influx transporters ie transport substrates from blood into organs and cells. OATPs ...
June 12, 2023
Mechanisms and consequencesPermeability-glycoprotein is known as P-glycoprotein or P-gp or multidrug resistance protein (MDR1/2); it has a large and versatile ...
May 29, 2023
Mechanisms and consequencesThe Sodium Vitamin C Transporters (SVCTs) regulate vitamin C homeostasis (system stability) such that excessive intakes result in ...
May 22, 2023
Mechanisms and consequencesMATE1/2 (Multi drug and toxin exclusion transporters MATE1 and MATE2) are major efflux transporters involved in the hepatic ...
May 15, 2023
Mechanisms and consequencesBCRP (Breast Cancer Resistance Protein) seems to be an initial defence against environmental insults such as phototoxic skin ...
